In this study，an approach towards the optimization of the electrical conductivity of laser-induced graphene(LIG)was investigated by systematically analyzing the effects of varying laser parameters and in-situ doping with multi-walled carbon nanotubes(MWCNTs)on the resistance characteristics and microstructure of LIG. The experimental results showed that the resistance of the LIG decreased as the laser energy density increased from 5 to 10 J/mm2. The minimum resistance of ~1 kΩ was obtained at a laser power of 30 W and an energy density of 8 J/mm2. After in-situ doping was performed with different mass ratios of MWCNTs to poly(amic acid)(PAA)，scanning electron microscopy(SEM)revealed that the composite LIG formed a more complete conductive network. As a result，the resistance of the composite LIG was further reduced to a minimum of 0.5 kΩ，which is lower than that of pristine LIG. These findings indicated that an effective processing window could be established to optimize the conductivity of LIG by regulating the laser parameters and dopant content. Thus，this study provided a practical reference on the fabrication of LIG-based flexible resistive strain sensors and the optimization of their performance.