The infrared focal plane readout circuit is mainly used for the communication between the focal plane array and the subsequent signal processing. This paper proposes a buffer module for IRFPA ROIC, including the column buffer, high-performance output buffer, and the corresponding bias circuit. The buffers use the unity gain amplifier architecture and the effective drive of different loads can be realized while the static power consumption is low through the optimization design of amplifier. The module has been applied to a 640×512 MW IRFPA ROIC with 15μm pixel pitch and taped out by CSMC 0.5μm DPTM CMOS process. The simulation results show that the open loop gain of column buffer is 40.00dB, the unit gain bandwidth is 48.17MHz(10pF).The output buffer can realize the rail-to-rail input and the open loop gain is 39.68dB, the unit gain bandwidth is 46.08MHz, the readout rate is up to 20MHz and power consumption is 16.02mW (25pF∥5.1kΩ). The test pin which is the input port of the module can help verify chip functions in the ROIC wafer testing. By adjusting the test port, the test results are in good agreement with the simulation results, which verifies the feasibility of the design of the buffer module.